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LVLUP Health

PEA

PEA

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PEA

THE NATURAL PAIN KILLER AND ANTI-INFLAMMATORY

Palmitoylethanolamide (PEA) is a naturally occurring fatty acid that has been studied to show neuroprotective, anti-inflammatory, cardioprotective and analgesic pain relief properties.

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Description

PEA is a naturally occurring fatty acid found mainly in egg yolks and mothers milk, but is also naturally produced by the body in response to pain.

As a supplement, it has been studied to show neuro-protectiveanti-inflammatory, and analgesic (pain-relieving) properties.

PEA Belongs to the endocannabinoid family therefore acts on similar receptors to cannabis oil; it is a fully legal and similarly efficacious alternative to CBD oil.

In several studies focused on management of chronic pain, PEA was shown to have potent anti-inflammatory and analgesic effects, therefore and may help with the treatment of chronic pain.

PEA is being used in functional medicine for many disease states including fibromyalgia, osteoarthritis, MS, carpal tunnel syndrome and autism.

It also shows potent neuroprotective and cardioprotective effects due to it being a fatty acid, fats have an affinity for the brain and heart (fat using organs) therefore may help with CNS and Neurological inflammatory issues, as well are cardiac issues such as myocarditis and pericarditis. 

It also may help with histamine issue and MCAS issues, as it is a strong anti-histamine, mast cell stabilising ingredient. 

 

Each bottle contains 60 capsules; 30 serves.

  • Conditions with evidence of Benefit with PEA

    1. Arthritis – osteoarthritis & rheumatoid athritis
    2. Fibromyalgia
    3. Peripheral neuropathies – diabetic neuropathy & chemotherapy-induced peripheral neuropathy
    4. Carpal tunnel syndrome
    5. Opioid Tolerance and Hyperalgesia
    6. Low back pain – herniated disc disease, failed back surgery syndrome, other
    7. Sciatic pain
    8. Dental pain
    9. Neuropathic pain – related to stroke & multiple sclerosis
    10. Inflammatory Bowel Disease
    11. Chronic pelvic pain
    12. Shingles pain (postherpetic neuralgia)
    13. Vaginal pain (vulvadynia)
    14. Post-operative dental surgery pain
    15. Traumatic Brain Injury/Chronic Traumatic Encephalopathy

Dosage

Taken once per day with or without food.500mg per capsule/serve0.5-1.5g per day recommended dose (1-3 capsules)

Testimonials

"I have been trying to heal my gut for years and tried just about every supplement possible to heal my gut but nothing seemed to make much of a difference. Then I was introduced to Ultimate GI and given a chance to try it. Even though I trusted the person who recommended it I still was a little sceptical because I'd tried so many other supplements. But I gave it a go and Wow. Within a matter of weeks I saw a very noticeable improvement in my digestion I no longer reacted to foods the way I used to. In fact for the first time in years I was able to eat and enjoy Christmas deserts without feeling awful like I usually would. I've also become far less reactive to foods and my digestive issues and lethargy I once had after eating have basically gone all together. Best decision I made to try this supplement. Well and truly lives up to its name. If you're someone like me who has tried just about every supplement then give this one a try. You will be glad you did."

Isaac B

I was skeptical of this product because I’d tried heaps of different gut supplements before that didn’t work, but after using GI Repair for only 3 days I noticed a huge difference in my reflux and bloating! The issue is completely fixed now! thank you guys!

Joseph F

“I love this product. I haven’t had an upset belly in weeks. Most of my pain is also gone which I wasn’t expecting. So so good!”

Molly D

Great product. Highly recommend. Quick turnaround time on orders.

Scott M

"I used to get a lot of pain and discomfort after certain foods, but I can even enjoy dairy now!!!"

Estelle T

"Wheat, dairy and a many other foods no longer effect me! this is awesome because they used to cause me so much pain and bloating, and now, nothing!! Soo happy!"

Lauren V

"This product has completely changed my digestion, I literally never get bloated or sluggish anymore. And surprisingly the asthma I’ve had since 6yrs old has disappeared. Nothing else I’ve tried has been so anti-inflammatory and healing. WOW!"

Lance S

"Have actually been using BPC157 for a few years due to number of different injuries. Its so great to finally find a reputable company. Keep up the good work guys."

Chris F

RESEARCH

Studies

https://www.ncbi.nlm.nih.gov/pmc/?term=palmitoylethanolamide 

Brcic, L., Brcic, I., Staresinic, M., Novinscak, T., Sikiric, P., & Seiwerth, S. (2009). Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society, 60 Suppl 7, 191–196.

Cerovecki, T., Bojanic, I., Brcic, L., Radic, B., Vukoja, I., Seiwerth, S., & Sikiric, P. (2010). Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat. Journal of Orthopaedic Research, 28(9), 1155–1161.

Chang, C. H., Tsai, W. C., Hsu, Y. H., & Pang, J. H. S. (2014). Pentadecapeptide bpc 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules, 19(11), 19066–19077.

Chang, C. H., Tsai, W. C., Lin, M. S., Hsu, Y. H., & Su Pang, J. H. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 110(3), 774–780.

Gjurasin, M., Miklic, P., Zupancic, B., Perovic, D., Zarkovic, K., Brcic, L., … Sikiric, P. (2010). Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury. Regulatory Peptides, 160(1–3), 33–41.

Gwyer, D., Wragg, N. M., & Wilson, S. L. (2019). Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research, 377(2), 153–159.

Perovic, D., Kolenc, D., Bilic, V., Somun, N., Drmic, D., Elabjer, E., … Sikiric, P. (2019). Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research, 14(1), 1–12.

Pevec, D., Novinscak, T., Brcic, L., Sipos, K., Jukic, I., Staresinic, M., … Sikiric, P. (2010). Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application. Medical Science Monitor, 16(3), 81–88.

Seiwerth, S., Sikiric, P., Grabarevic, Z., Zoricic, I., Hanzevacki, M., Ljubanovic, D., … Kolega, Z. (1997). BPC 157’s effect on healing. Journal of Physiology Paris, 91(3–5), 173–178.

Sever, A. Z., Sever, M., Vidovic, T., Lojo, N., Kolenc, D., Vuletic, L. B., … Sikiric, P. (2019). Stable gastric pentadecapeptide BPC 157 in the therapy of the rats with bile duct ligation. European Journal of Pharmacology, 847(January), 130–142.

Sikiric, P. (1999). The pharmacological properties of the novel peptide BPC 157 (PL-10). Inflammopharmacology, 7(1), 1–14.

Sikiricc, P., Petek, M., Rucman, R., Seiwerth, S., Grabarevic, Z., Rotkvic, I., … Karakas, I. (1993). A new gastric juice peptide, BPC. An overview of the stomach-stress-organoprotection hypothesis and beneficial effects of BPC. Journal of Physiology – Paris, 87(5), 313–327.

Sikiric, P., Seiwerth, S., Kolenc, D., Grgic Klinicka bolnica, T., Duh, S., Rucman, R., … Vlainic, J. (2018). Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications Article in DNA research: an international journal for rapid publication of reports on genes and genomes · May 2016 CITATIONS 12 READS 793 Genetic and epigenetic biomarkers of innate immunity in COPD and lung cancer View project BPC 157

Staresinic, M., Sebecic, B., Patrlj, L., Jadrijevic, S., Suknaic, S., Perovic, D., … Sikiric, P. (2003). Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research, 21(6), 976–983. [/expand]