His Main
Synergistic enzyme and botanical complex supporting histamine metabolism, mast cell stability, and daily resilience for sensitive individuals.
      His Main
      His
      His
      His

      Hista-Resist

      Targeted Enzyme and Botanical Support for Histamine Balance

      In Stock
      DAO Enzyme Support
      Mast Cell Stabilization
      Botanical Polyphenol Complex
      Digestive Resilience Formula
      $89.99 USD
      Add to Cart
      Free Shipping Over $300
      30 Servings
      90 Capsules
      Synergistic enzyme and botanical complex supporting histamine metabolism, mast cell stability, and daily resilience for sensitive individuals.

      Targeted Enzyme and Botanical Support for Histamine Balance

      LVLUP Health Hista-Resist is designed for individuals seeking advanced nutritional support for balanced histamine responses. This comprehensive formula delivers 20,000 HDU of DAO2 enzyme to help break down dietary histamine before absorption. Botanical polyphenols – including Quercetin, EMIQ, Luteolin, Bromelain, and Baicalin – work in concert to help maintain mast cell stability and moderate immune signaling. Essential cofactors Vitamin C, Copper, and B2 further support enzymatic pathways crucial for histamine clearance. Backed by transparent dosing and rigorous manufacturing standards, Hista-Resist offers a multi-faceted approach to everyday histamine management.

      His
      8.4 mg
      DAO2
      DAO2 is a highly active source of diamine oxidase enzyme extracted from pig kidneys. It supports the breakdown of food-derived histamine within the digestive tract - particularly useful when natural enzyme levels are low due to genetic or environmental factors.
      21 mg
      Vitamin B2
      Vitamin B2, also known as riboflavin, plays a crucial role in converting calories into energy and maintaining healthy cells. It's commonly found in foods like dairy, eggs, lean meats, and leafy vegetables. As part of the B vitamin family, it's often included in supplements for energy support, brain health, and overall wellness.
      90 mg
      Vitamin C
      Vitamin C, also known as ascorbic acid, is a water-soluble vitamin celebrated for its role in immune support and skin health. Its applications range from cellular protection to aiding collagen synthesis and enhancing iron absorption. This versatility makes it a staple in many supplement formulas.
      90 mg
      Luteolin
      Luteolin is a natural flavonoid found in plants like celery, parsley, and chamomile. Known for its potential benefits on brain, gut, and immune health, it's often used in supplements aimed at calming the digestive system and balancing histamine levels.
      120 mg
      Rutin
      Rutin is a plant flavonoid found in foods like buckwheat, apples, and citrus peels. It's valued for its role in supporting heart, brain, and vascular health. Known for aiding digestion and regulating histamine response, rutin is a versatile supplement component.
      150 mg
      Baical Skullcap
      Baical skullcap is a yellow-rooted herb used in East Asian wellness practices. Its main compound, baicalin, is valued for supporting immune health, brain function, and balancing histamine levels.
      180 mg
      Pineapple Enzyme
      Bromelain, found in pineapple stems, is known for its protein-digesting abilities. It’s often used to aid digestion, promote muscle recovery, and support your immune system in managing stress. This enzyme also acts as a natural anti-inflammatory and anti-histamine, making it useful for those concerned about histamine reactions and physical discomfort.
      210 mg
      PEA
      Palmitoylethanolamide, or PEA, is a naturally occurring fatty molecule in your body. It increases during times of stress or discomfort. Though found in foods like peanuts and egg yolks, these sources often fall short when the body's demands are high. As a supplement, PEA is popular for supporting nerve comfort and helping maintain balance during physical or emotional stress.
      210 mg
      Quercetin Combo
      Quercetin Combination blends quercetin with nutrients like bromelain, vitamin C, or resveratrol to improve absorption and amplify antioxidant effects. These formulas often target immune support, inflammation, and overall wellness.
      300 mg
      Black Seed Oil Extract
      Black Seed Oil Extract, derived from the seeds of Nigella sativa, has historical roots in traditional medicine across Asia and the Middle East. Known for its potential benefits in supporting gut health, immune function, and allergy response, it's recognized today for its active component, thymoquinone, which is being studied for its role in reducing oxidative stress and modulating immune responses.
      12 mg
      Copper Citrate
      Cupric citrate, commonly known as copper citrate, is a highly absorbable form of copper found in many supplements. This essential mineral plays a key role in enzyme activity and overall cellular health. Its benefits range from supporting energy production and DNA synthesis to aiding in antioxidant defense and histamine metabolism.
      3
      Capsules
      Serving Size
      90
      Capsules
      Package Contents

        How It Works

        Immediate Histamine Breakdown

        Upon ingestion before meals, the DAO2 enzyme acts within the digestive tract by breaking down dietary histamine molecules before they can be absorbed systemically. This first-line mechanism helps limit how much intact histamine reaches circulation from food sources.

        Image