Urolithin A a the POSTBIOTIC metabolite of huge benefit to human health and promotes the growth and function of...
Akkermansia muciniphila, a powerful keystone PROBIOTIC that support metabolic and gut health... 
and the PREBIOTIC polyphenolic blend supports the growth of the Akkermansia and other beneficial bacterial species.

This PRE+PRO+POST Biotic blend delivers a synergy that is unmatched and unseen in the supplement space.

Akkermansia muciniphila

Akkermansia muciniphila (AKK) is a keystone bacterial strain found in the human gastrointestinal tract that has garnered significant attention in recent years due to its potential health benefits. This microorganism plays a crucial role in maintaining gut health and has been linked to various positive health outcomes.

Metabolic Health
AKK has been associated with improved metabolic health, including:

• Enhanced leanness
• Better blood sugar control
• Increased resistance to obesity
• Reduced risk of type 2 diabetes

Gut Health
The primary mechanism by which AKK benefits our health is through its interaction with the intestinal mucus layer:

1. AKK consumes mucus
2. This stimulates increased mucus production
3. The result is a strengthened intestinal wall
4. Overall gut health is enhanced

Mechanisms of Action

AKK's beneficial effects on health are multifaceted:

1. Gut Barrier Integrity: AKK strengthens the intestinal wall by stimulating mucin production and maintaining tight junctions between epithelial cells
   
2. Immune Modulation: It produces antimicrobial peptides within the mucin layer, contributing to gut immunity.
3. Metabolic Regulation: AKK has been shown to improve glucose tolerance and attenuate adipose inflammation.
4. Intestinal Stem Cell Proliferation: Recent research indicates that AKK secretes proteins that promote intestinal stem cell activity, contributing to gut health and regeneration.

In conclusion, Akkermansia muciniphila represents a promising avenue for improving gut health and overall well-being. Its synergistic relationships with compounds like Urolithin A and prebiotic polyphenols further enhance its potential as a next-generation probiotic. As research continues to expand, AKK may play an increasingly important role in preventive and therapeutic approaches to various health conditions.

Urolithin A

Urolithin A IS  cutting-edge compound revolutionizing gut health and cellular rejuvenation. This remarkable metabolite, derived from ellagitannins found in pomegranate, chokeberry, cranberry and other polyphenolic foods, is produced by beneficial gut bacteria, including the Akkermansia muciniphila.

Urolithin-A supports mitochondrial function, enhances muscle strength and endurance, and promotes overall metabolic wellness.

By combining Urolithin A with prebiotic ellagitannins, we create an optimal environment for Akkermansia to thrive, further amplifying the benefits for your gut microbiome and whole-body health. Experience the transformative effects of this scientifically-backed supplement, designed to support healthy aging, improve muscle performance, and fortify your body's natural defenses from the inside out.

Synergistic Relationships

Urolithin A and AKK
Urolithin A, a metabolite derived from ellagitannins, has been shown to enhance the function of Akkermansia muciniphila in the gut. This synergistic relationship provides multiple benefits:

• Improved gut barrier function
• Enhanced mitochondrial health
• Potential increase in muscle strength
• Possible extension of cellular lifespan
  

Urolithin-A significantly enhances the efficacy of Akkermansia muciniphila (AKK) by promoting its growth and abundance in the gut, creating a favorable environment for its beneficial effects.

This synergy improves gut barrier integrity, which helps prevent harmful substances from entering the bloodstream, and leads to better metabolic outcomes, including improved glucose tolerance and reduced inflammation.

Additionally, Urolithin-A positively modulates the overall gut microbiota composition, supporting the growth of beneficial bacteria while inhibiting harmful strains. The combination of Urolithin-A and AKK also exhibits anti-inflammatory properties and supports mitochondrial health, potentially improving cellular energy production.

Overall, this partnership amplifies the health benefits associated with both compounds, making it a promising approach for enhancing gut health and metabolic wellness.

Prebiotic Polyphenols
Certain polyphenols act as prebiotics, specifically promoting the growth of Akkermansia muciniphila. A blend of prebiotic polyphenols can further support AKK's growth and function, including:

1. Apple pectin
2. Chokeberry
3. Cranberry

These ingredients are rich in ellagitannins, which can be fermented by our microbiome to produce Urolithin A, further enhancing the synergistic effects of this product.